一對十二歲的雙胞胎男孩 Zack(Dylan Sprouse)和Cody(Cole Sprouse)還有他們的媽媽是這所波斯頓高檔Tipton酒店的長期住客。在這里，他們認識了新朋友London(Brenda Song)和Maddie(Ashley Tisdale)。Zack和Cody接二連三的惡作劇把Tipton旅館變成了他們的游樂場。在搞笑、搗蛋、引發混亂的同時，也帶著London和 Maddie瘋了一回。Outrageous shenanigans ensue when 12-year-old twin boys Zack (Dylan Sprouse) and Cody (Cole Sprouse) turn the upscale Boston hotel where they live (The Tipton) into their own personal playground. Living in a suite with their mom Carey, the boys often take their new friends London and Maddie along for the…